Amid the threat of nuclear proliferation, global warming and terrorism, the earth's creator tries to reconnect with mankind by returning to the planet and hosting his own variety show.

Pressured by his deceased mother's ghost to return home to the family he abandoned, a former addict grabs a bag of pills and a sack of marijuana and hits the road to Shreveport.

Subversive humor and childlike wonder based on both Reubens' original stage show, "The Pee-wee Herman Show," and the Emmy-winning Saturday morning TV show, "Pee-wee's Playhouse."

In Los Angeles, Andy Conners works in Fearless Records selecting new talents. Andy is in love and engaged to Lauren Baker for one year but he is unable to satisfy Lauren in bed. Further, he has never told Lauren that he loves her. Andy tells his problem to his best friend Layne Wilson and they research how to satisfy Lauren with an orgasm. Meanwhile Lauren is promoted in her company but she needs to be transferred to Chicago. When her colleague Daniel Meltzer comes to Los Angeles to convince Lauren to move to Chicago, they discover that they had been friends in the childhoods. Andy misunderstands the relationship between Daniel and Lauren and believes that she is cheating on him. Will Andy lose Lauren to Daniel?

Brüno is a gay Austrian fashion guru. He has his own fashion based television show, Funkyzeit, the most popular German-language show of its kind outside of Germany. After he disgraces himself in front of his Funkyzeit fan base, he is ruined in German speaking Europe. He decides that in his quest for worldwide fame, he will move to Los Angeles and reinvent himself. Accompanying him to the US is Lutz, his former assistant's assistant. Lutz is the only person left in his circle that still believes in Brüno's greatness. Brüno goes through one reinvention of himself after another, ultimately straying to areas far removed from his own self. Perhaps when Brüno finds an activity that he truly does love, he will also find that über-fame he so desperately desires.

When an overachieving high school student decides to travel around the country to choose the perfect college, her overprotective cop father also decides to accompany her in order to keep her on the straight and narrow.